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Vanessa Sperandio Ph.D. /Professor

UT Southwestern Medical Center

Enterohemorrhagic E. coli (EHEC) sings: pour some sugar on me

Vanessa Sperandio Ph.D. /Professor

演讲题目:Enterohemorrhagic E. coli (EHEC) sings: pour some sugar on me

UT Southwestern Medical Center

Vanessa Sperandio is a professor in the Departments of Microbiology and Biochemistry at UT Southwestern Medical Center. She got her bachelor’s degree in biology and her master’s degree and doctorate  in molecular genetics, under the mentorship of Wanderley Dias da Silveira at the State University of Campinas (UNICAMP) in Brazil. Sperandio received a fellowship from the Brazilian government to conduct part of her doctoral research at the University of Maryland School of Medicine, in the laboratory of James B. Kaper, Ph.D., where she would later pursue her postdoctoral training. She joined the faculty in the Microbiology Department at UT Southwestern in 2001.

Sperandio was a Pew Latin American Fellow in the Biomedical Sciences (1997), an Ellison Medical Foundation New Scholar (2004), a Burroughs Wellcome Fund Investigator in the Pathogenesis of Infectious Disease (2006), and a Kavli Frontiers of Science Fellow (2007). She is the recipient of the 2015 Eli Lilly and Co.-Elanco Research Award, and a winner of the 2014 GlaxoSmithKline Discovery Fast Track Challenge. In 2013, she was elected a fellow of the American Academy of Microbiology. Her research investigates chemical, stress, and nutritional signaling at the interface among the mammalian host, beneficial microbiota, and invading bacterial pathogens. The main tenet of research in her laboratory is the study of how bacterial cells sense several mammalian hormones, leading to rewiring and reprogramming of bacterial transcription toward host and niche adaptation. She has also identified several bacterial receptors to mammalian hormones and reported that invading pathogens hijack these interkingdom signaling systems to promote virulence expression. She also translated these basic science concepts into strategies to develop novel approaches to antimicrobial therapy.

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