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举办会议及论坛超过百场 邀请海内外院士超过50名 教授PI专家授课超过1000名 总参会人数超过10万人
2018-09-14至2018-09-15 南京
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陆剑 研究员

北京大学生命科学学院

The origins, convergent and divergent evolution of metazoan microRNAs

陆剑 研究员

演讲题目:The origins, convergent and divergent evolution of metazoan microRNAs

北京大学生命科学学院

Dr. Jian Lu received his BS and MS degrees from Peking University in 1999 and 2002, respectively. He earned his Ph.D. degree in Ecology and Evolution in 2008 from the University of Chicago under the guidance of Dr. Chung-I Wu. In his Ph.D. study, Jian used a combination of computational and experimental approaches to study the origin and subsequent evolution of Drosophila genomes. After his Ph. D. study, Jian moved to Cornell University and did his postdoc under the supervision of Dr. Andy Clark. At Cornell, Jian studied the regulatory roles of microRNAs in the innate immune response of Drosophila. He extended this work to humans and primate ancestors, showing that genes regulated by miRNAs overall have greater expression variation both among human ethnic groups and among primate species. He also pursued a project on the population dynamics of piRNAs and the transposons that they regulate. Jian set up his own lab at Peking University since from 2013. His lab is currently combining functional and evolutionary genomics to study gene regulation mediated by post-transcriptional regulations such as RNA modifications and small-RNA-mediated regulations in both flies and humans. The ultimate goal of his research is to understand how genotypes affect phenotypes and how natural selection operates during this process.

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