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举办会议及论坛超过百场 邀请海内外院士超过50名 教授PI专家授课超过1000名 总参会人数超过10万人
2018-11-23至2018-11-24 上海
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已确认嘉宾Confirmed Guests

翁锦生 教授

美国安德森癌症中心

翁锦生 教授

美国安德森癌症中心

教育背景   
  医学学士  南昌大学,预防医学,

医学硕士  中山大学, 临床医学内科学

医学博士  德州农工大学医学中心, 肿瘤和干细胞系

    

工作经历
● 1994-1999  临床检验师,广东江门中心医院

●  2007-2008  博士后研究者, 贝勒医学院

●  2008-2011  博士后研究者, 美国安德森肿瘤中心

●  2011-现在  研究指导, 美国安德森肿瘤中心

    

   学会会员

       ●  美国生物化学与分子生物学学会副会员

       ●  美国肿瘤学会副会员

●  美国肿瘤学会会员

●  美国血液病学会会员

●  美国免疫学会会员

●  美国肿瘤免疫治疗协会会员

 

奖励

    ● 2004  美国生物化学与分子生物学学会研究生旅行奖

    ● 2005  德州农工大学医学部新生医学讨论会海报第一名

    ● 2006  美国生物化学与分子生物学学会研究生旅行奖

    ● 2011  美国血液病学会优秀文摘奖

    ● 2011  Margaret L. Kripke 特别优秀肿瘤免疫学者奖

    ● 2014  美国免疫学会新教师旅行奖

     

 专利

    TCL1 多肽在肿瘤免疫治疗中的应用(WO 2013075105 A3)

    TCL1 多肽在肿瘤免疫治疗中的应用(US 20140348902 A1)

 

 研究基金

   美国国立卫生研究院多发性骨髓瘤SPORE事业基金(2013-2014, 第一负责人)

   国际多发性骨髓瘤基金会新研究者基金(2014,第一负责人)  

   美国女士白血病基金(2014,第一负责人)

   美国国立卫生研究院多发性骨髓瘤SPORE事业基金(2014-2015, 第一负责人)

 

   发表文章

     1. Weng, J., Baio FE, Moriarty KE, Torikai H, Wang H, Liu Z, Maiti S, Gwak D, Popescu MS, Cha SC, Cooper LJ, Neelapu SS, Kwak LW. IL-15 enhances the anti-tumor effect of human antigen-specific CD8 T cells by cellular senescence delay OncoImmunology 2016 Oct 7; 5(12):e1237327. (IF: 5.503, First and corresponding author)


     2. Weng, J., Moriarty KE, Baio FE, Chu F, Kim SD, He J, Jie Z, Xie X, Ma W, Qian J, Zhang L, Yang J, Yi Q, Neelapu SS, Kwak LW. Targeting B-cell malignancies through human B-cell receptor specific CD4 T cells OncoImmunology 2016 Sep 19;5(11):e1232220. (IF: 5.503, First and corresponding author)


     3. Weng, J., Rawal, S., Chu, F., Park, H.J., Sharma, R., Delgado, D.A., Fayad, L., Fanale, M., Romaguera, J., Luong, A., et al. TCL1: a shared tumor-associated antigen for immunotherapy against B-cell lymphomas. Blood 2012. 120:1613-1623. (IF: 15.132)


     4. Weng, J., Cha, S.C., Matsueda, S., Alatrash, G., Popescu, M.S., Yi, Q., Molldrem, J.J., Wang, M., Neelapu, S.S., and Kwak, L.W. Targeting human B-cell malignancies through Ig light chain-specific cytotoxic T lymphocytes. Clin Cancer Res 2011. 17:5945-5952. (IF: 10.199)


     5. Weng, J., Neelapu, S.S., Woo, A.F., and Kwak, L.W. Identification of human idiotype-specific T cells in lymphoma and myeloma. Curr Top Microbiol Immunol 2011. 344:193-210. (IF: 5.829, First and corresponding author)


     6. Weng, J., Luo, J., Cheng, X., Jin, C., Zhou, X., Qu, J., Tu, L., Ai, D., Li, D., Wang, J., et al. Deletion of G protein-coupled receptor 48 leads to ocular anterior segment dysgenesis (ASD) through down-regulation of Pitx2. Proc Natl Acad Sci U S A 2008. 105:6081-6086. (IF: 9.504)


     7. Weng, J., Wang, J., Hu, X., Wang, F., Ittmann, M., and Liu, M. PSGR2, a novel G-protein coupled receptor, is overexpressed in human prostate cancer. Int J Cancer 2006. 118:1471-1480. (IF: 7.360)


     8. Weng, J., Wang, J., Cai, Y., Stafford, L.J., Mitchell, D., Ittmann, M., and Liu, M. Increased expression of prostate-specific G-protein-coupled receptor in human prostate intraepithelial neoplasia and prostate cancers. Int J Cancer 2005. 113:811-818. (IF: 7.360)


     9. Weng, J., Ma, W., Mitchell, D., Zhang, J., and Liu, M. Regulation of human prostate-specific G-protein coupled receptor, PSGR, by two distinct promoters and growth factors. J Cell Biochem 2005. 96:1034-1048. (IF: 2.959)


     10. Weng, J., Wang, J., Cai, Y., Penland, R., Liu, M., and Ittmann, M. The prostate-specific G-protein coupled receptors PSGR and PSGR2 are prostate cancer biomarkers that are complementary to alpha-methylacyl-CoA racemase. Prostate 2006. 66:847-857. (IF: 3.347, co-first author)


     11. Yi T, Weng J, Siwko S, Luo J, Li D, Liu M. LGR4/GPR48 inactivation leads to aniridia-genitourinary anomalies-mental retardation syndrome defects. J Biol Chem 2014. 289(13): 8767-80. (IF: 4.010)


     12. Matsueda, S., Wang, M., Weng, J., Li, Y., Yin, B., Zou, J., Li, Q., Zhao, W., Peng, W., Legras, X., et al. Identification of prostate-specific G-protein coupled receptor as a tumor antigen recognized by CD8(+) T cells for cancer immunotherapy. PLoS One 2012. 7:e45756. (IF: 2.766)


     13. Siwko, S., Lai, L., Weng, J., and Liu, M. Lgr4 in ocular development and glaucoma. J Ophthalmol 2013; 2013:987494. (IF:1.680)


     14. Mitchell, D.C., Abdelrahim, M., Weng, J., Stafford, L.J., Safe, S., Bar-Eli, M., and Liu, M. Regulation of KiSS-1 metastasis suppressor gene expression in breast cancer cells by direct interaction of transcription factors activator protein-2alpha and specificity protein-1. J Biol Chem 2006. 281:51-58. (IF:4.010)


     15. Rodriguez M, Luo W, Weng J, Zeng L, Yi Z, Siwko S, Liu M. PSGR promotes prostatic intraepithelial neoplasia and prostate cancer xenograft growth through NF-κB. Oncogenesis. 2014; 3:e114. doi: 10.1038/oncsis.2014.29 (IF: 4.722)


编书

 Weng, J., Neelapu, S., Woo, A., and Kwak, L. 2011. Identification of Human Idiotype-Specific T Cells in Lymphoma and Myeloma. In Cancer Immunology and Immunotherapy. G. Dranoff,

            editor: Springer Berlin Heidelberg. 193-210.

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